IL17A and psoriasis: This finding was related to other affected top canonical pathways, including: “Differential regulation of cytokine production in intestinal epithelial Cells by IL-17A and IL-17F” (p < 1.26 × 10−7), “Differential regulation of cytokine production in macrophages and T Helper cells by IL-17A and IL-17F” (p < 5.65 × 10−7), and “Role of IL-17A in psoriasis” (p < 2.31 × 10−6) (Figure 4A and Figure 5).