IFNG and asthma: The mechanism by which the adipokines could have a role in the pathogenesis of asthma is not clearly defined; on the one hand, it has been suggested that it participates in the TH1-type inflammation since it correlates with the levels of IFN- γ and it has been described that in the presence of high leptin levels, only asthmatic obese children exhibited a TH1 polarisation with elevated IFN-γ levels and more severe asthma [26].