Cox regression adjusted for BMI showed that the CYP27B1 rs4646536 (p = 0.0411; HR = 2.52; CI95% = 1.04–6.12), CYP24A1 rs6068816 (p = 0.0048; HR = 8.77; CI95% = 1.94–39.7), and VDR rs7975232 (p = 0.0002; HR = 3.08; CI95% = 1.71–5.54) polymorphisms were significantly associated with PFS in patients with non-resected NSCLC (Plikelihood ratio test = 0.00006) (Table 8). This evidence concerns the gene CYP24A1 and non-small cell lung carcinoma.