The selected genetic variants involved in the obesity risk were SEC16 Homolog B (SEC16B, endoplasmic reticulum export factor) rs543874, DnaJ heat shock protein family (Hsp40) member C27 (DNAJC27)_rs713586, CDK5 regulatory subunit-associated protein 1-like 1 (CDKAL1)_rs9356744, transcription factor AP-2 Beta (TFAP2B)_rs2206277, BDNF_rs6265, myosin light chain-2 (MYL2)_rs3782889, olfactomedin-4 (OLFM4)_rs9568856, FTO_rs1421085, MC4R_rs6567160, and GIPR_rs1444988703 (Table 3). This evidence concerns the gene SEC16B and obesity due to melanocortin 4 receptor deficiency.