They noticed that the action of grifolin on human nasopharyngeal carcinoma (NPC) CNE1, CNE1-LMP1, and C666-1 cells occur notably via the attenuation of glycolytic flux and the recovery of mitochondrial OXPHOS function by inhibiting DNMT1 expression and activity as well as its mitochondrial retention in NPC cells [100]. The gene discussed is DNMT1; the disease is nasopharyngeal carcinoma.