GRP and neoplasm: All three radiopharmaceuticals, 99mTc-AuNP–Lys3-bombesin, 99mTc-AuNP–mannose and 99mTc-AuNP–c[RDGfK(C)] were found to exhibit suitable properties for be employment as potential target-specific agents for the molecular imaging of GRP-r-positive tumors, SLN detection, and tumor αvβ3 expression, respectively.