TLR3 and lymphoma: Han et al. prepared a chitosan nanoparticle (CH-NP)-based platform to bypass the ex vivo manipulation and stimulate an immune response through the active transport of polyinosinic-polycytidylic acid sodium salt (poly I:C) to aim at Toll-like receptor 3 (TLR3) in endosomes; this platform might be suitable in lymphoma treatment [166].