It appears that the antibodies against CagA can directly cross-react with the surface antigen of the blood vessel wall [103], induce lymphocyte proliferation, and provoke the host to release several pro-inflammatory agents, such as the aforementioned IL-1, TNF-α, IL-1, fibrinogen, and CRP [104,105]; as stated, such pro-inflammatory mediators are also related with MetS [106]. This evidence concerns the gene CRP and metabolic syndrome.