Interestingly, the MME with the sequence LGPWRSGGVL that is 70% homologous to the M19 CD8+ T cell neo-epitope described by Kreiter et al. was found in some Bacteroidales, Prevotella and Muribaculacee species, and its abundance increased over time in treated mice, which showed a reduced tumor volume with respect to control animals. This evidence concerns the gene CD8A and neoplasm.