Comparison of hematological profiles between patients with relatively mild disease and those with ARDs shows marked elevation in CD14+, IL-1b-producing monocytes in the peripheral circulation [35], infiltration of monocytes and neutrophils into the respiratory tract [35], as well as increased IL-6 and IL-1b in the serum of ARDs patients [30,32,35,36,37]. This evidence concerns the gene IL6 and acute respiratory distress syndrome.