To assess whether GR and KLF15 occupy ICP27 promoter sequences during productive infection, Neuro-2A (Figure 8A) and Vero (Figure 8B) cells were infected with HSV-1 and the cells harvested at 0, 4, 8, and 16 h post infection (hpi) for ChIP studies. This evidence concerns the gene NR3C1 and infection.