However, CD45.1 CD8 T cells isolated from the livers of mice infected with 108 pfu Ad-HBV-Luc showed still increased expression of PD1 and TOX and reduced expression of KLRG1 and GzmB, compared to their counterparts isolated from livers after 107 pfu Ad-HBV-Luc infection (Figure 5E). Here, CD8A is linked to infection.