IFNA2 and infection: Considering that we used 0.5 MOI of HCoV-OC43, this outcome is consistent with the previous report regarding the effect of IFN-α-2b on SARS-CoV replication in Vero E6 cells; treatment with 1000 IU/mL of IFN-α-2b reduced about 0.5 log decrease in virus titers at 72 h after infection with 0.001 MOI of SARS-CoV [46].