Innate immune responses, i.e., antiviral (IFN-α), pro-inflammatory (IL-6), inflammatory (haptoglobin) and anti-inflammatory (IL-10) responses, were investigated in sera and/or BALF sampled during the time course of the study, and compared in the context of PRRSV and swIAV single infections versus the super-infection. This evidence concerns the gene IL10 and infection.