IL1B and colitis: Coriander EO exhibited anti-inflammatory effects in an in vivo model of colitis as determined by histo-pathologic evaluation and myeloperoxidase activity [72]; meanwhile, its main constituent linalool was found to inhibit the production of pro-inflammatory cytokines (e.g., TNF-α, IL-1β, IL-6, IL-8) in both in vitro and in vivo settings [73,74].