UBASH3A and infection: Additionally, both genes STS1 (Figure 5E) and STS2 (Figure 5F), which are enzymes for sesquiterpenes biosynthesis, were down-regulated by infection in cones of the Saaz (5.9 and 2.3 times), Sládek (2.2 and 13.8 times), and Agnus (2 and 3.3 times) cultivars.