BACH2 and acute kidney injury: In addition, BACH2 rs4388268 was consistently associated with a decreased eGFR in the discovery cohort with genome-wide significant association (β = −8.4, 95% CI −11.4–−5.4, p = 3.9 × 10−8) and with higher risk of the AKI-CTCAE with suggestive association (OR = 3.9, 95% CI 2.3–6.7, p = 7.4 × 10−7) (Table 3).