LDLR and familial hypercholesterolemia: In the second case, a 35-year-old (patient P10) got a diagnosis of “definite” familial hypercholesterolemia (DLCN score of 18, a history of myocardial infarction at the age of 24; mammary coronary artery bypass grafting at the age of 24; a second myocardial infarction at 34 years of age); rare variants were identified in exons 3 and 8 of the LDLR gene.