High levels of CXCL12 tumor expression associated with a significantly reduced risk of recurrence/metastasis, with a Hazard Ratio [95% confidence interval] of 0.12 [0.01–0.91], p = 0.041, which remained statistically significant after adjustment for Ki67 0.07 [0.01–0.62], p = 0.017, the global Weiss score 0.09 [0.01–0.92], p = 0.043, and age 0.13 [0.01–1.07], p = 0.05, as confounding factors. The gene discussed is CXCL12; the disease is neoplasm.