CXCL12 and adrenal cortex carcinoma: By stratifying the ACC-patient population according to the upper tertile value of CXCL12 mRNA distribution in low (≤169, 2−ΔΔCt) and high (>169, 2−ΔΔCt) expression, Kaplan–Meier survival analysis showed that CXCL12 significantly predict DFS (log rank = 0.022, Figure 3A), PFS (log rank = 0.010, Figure 3B), and OS (log rank = 0.048, Figure 3C).