STAT3 and non-small cell lung carcinoma: For example, Tabasum et al. reported that fisetin (10 μmol/l) inhibited the expression of β-catenin, NF-κB, EGFR, and STAT3 and decreased stem cell phenotype markers (CD44 and CD133) and TKI resistance in NSCLC cell lines (A549 and H1299) [236].