As revealed in Figure 12, pathways in cancer, estrogen signaling, proteoglycans, c-type lectin receptor signaling, microRNAs in cancer, VEGF signaling, arachidonic acid metabolism, autophagy, breast cancer, and cellular senescence are among the top signaling pathways that were proposed as being influenced by CE compounds (i.e., having the highest number of proteins targeted by CE compounds). The gene discussed is VEGFA; the disease is breast carcinoma.