PFKFB3 and inflammatory bowel disease: Ostrowski et al. identified a group of 15 genes (ANOS1, ANXA3, ATP9A, CACNA1E, COX6B2, FCGR1B, GALNT14, IL18R1, ITGB4, KLRF1, MMP9, OPLA, PFKFB3, S100A12, and UTS2R) in peripheral blood with the potential to discriminate between children with clinically active IBD and healthy donors, but not between adults with IBD and healthy donors [110].