Compared with 68Ga(DOTA-PSMA) and 68Ga(HBED-CC-PSMA) (68Ga-PSMA-11) [97,98], 68Ga-THP-PSMA is almost the same as these two radiopharmaceuticals in the aspect of tumor uptake, biodistribution, serum stability and pharmacokinetics, with a lower absorption in the spleen. Here, FOLH1 is linked to neoplasm.