Moreover, ACE A11860G (rs4343), ACE I/D (rs4340), AGT T174M (rs4762), AT1R A1166C (rs5186) and AGT M235T (rs699) gene polymorphisms were analyzed by Freitas et al., in 510 controls and 298 CAD patients from Portugal. The gene discussed is ACE; the disease is coronary artery disorder.