IFNG and COVID-19: Huang et al., noted that patients infected with COVID-19 had high levels of IL-1B and IFN-γ, while ICU patients had higher concentrations of granulocyte colony-stimulating factor (G-CSF), interferon gamma-induced protein 10 (IP-10), monocyte chemoattractant protein-1 (MCP-1), macrophage inflammatory protein-1 alpha MIP-1a and tumor necrosis factor alpha (TNF-α) than those who did not require ICU, suggesting that the cytokine storm was associated with disease severity [51].