Nading et al. examined the ER α and ERβ expression in 17 common nevi, 11 dysplastic nevi and 5 congenital nevi in pregnant individuals and compared them with 62 dysplastic nevi and 35 congenital nevi from non-pregnant patients, and found ERα was expressed solely in sebocytes of sebaceous glands, while ERβ expression was elevated in nevi, especially acquired nevi [38]. This evidence concerns the gene ESR2 and dysplastic nevus.