Lastly, as expected, no relation of PRL to arrhythmias was shown; in fact, the only association between PRL and the heart exists in the pathogenesis of peripartum cardiomyopathy, where a small antiangiogenic subfragment, 16-kDa prolactin, may provoke the disease by inducing endothelial damage [8]. The gene discussed is PRL; the disease is cardiac arrhythmia.