Studies on this receptor showed that HPV16-E6 reactive T cells are preferred in the CD45RA + CCR7 + T cell subpopulation of tumor infiltrating lymphocytes, peripheral blood lymphocytes, and T cells that are harvested from the draining of lymph nodes (T-LN) in patients with squamous cell carcinoma of the uterine cervix. The gene discussed is CCR7; the disease is neoplasm.