Similar topical studies of the influence of an extract or gel of Aloe vera on the skin wound-healing process in Wistar rats (with a wound made on the back) reported a significantly higher reduction of the scores (almost total wound closure) at 8 days for chitosan–glucan complex fibers reinforced with collagen and embedded with Aloe vera powder [34], 15 days for the pectine–allantoin film [19], and 15 days for insulin-loaded nanoemulsion with fresh Aloe vera gel in animals with induced diabetes [35]. This evidence concerns the gene INS and diabetes mellitus.