CRP and COVID-19: Other retrospective cohort studies from Wuhan, China, also reported reductions in inflammatory markers (CRP, IL-6, TNF-α) and ameliorated cardiac injury in patients with severe COVID-19 who had received a loading dose of 100 mg/kg bodyweight 6 hourly on the first day followed by 100 mg/kg 12 hourly for the following 5 days, relative to those who received standard therapy only [33,34].