In addition to MN-related degeneration disorders, given that PRMT8 modulates the visual cortical circuit as an epigenetic regulator [56], dendritic spine maturation as regulator of actin dynamics [15], and the control of context-dependent fear learning and anxiety behavior [14,15], it is possible that PRMT8 might also be involved in neurodevelopmental disorders. This evidence concerns the gene PRMT8 and neurodevelopmental disorder.