Other circular RNAs might act as oncogenes: circ_0132817 facilitates cell proliferation, migration, invasion, and glycolysis in neuroblastoma [54]; circPDE5A is upregulated in neuroblastoma tissues and cells and its silencing suppresses neuroblastoma cell proliferation, migration, invasion, and glycolysis in vitro and reduces tumor growth in vivo [55]; circular RNAs with oncogenic properties might even result from MYCN amplification in neuroblastoma cells [56]. This evidence concerns the gene MYCN and neoplasm.