This is an anti-TNF-α monoclonal antibody approved by Food and Drug Administration (FDA) and European Medicines Agency (EMA) for the treatment of rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn’s disease, plaque psoriasis, and hidradenitis suppurativa [13]. The gene discussed is TNF; the disease is Crohn disease.