IL17RC and infection: However, regarding specific genes, infection with the RNA1-mutated viruses provoked a differentiated immune response, which could be partly responsible for the decrease in mortality, hence the exclusive pkr upregulation at 2 days p.i., and il17rc downregulation at 3 days p.i., as well as an inability to induce gig1 at 2 days p.i. However, the expression of this gene reached the highest level at 3 days p.i.