LDLR and familial hyperaldosteronism: Familial hypercholesterolemia (FH) occurs due to an altered pathway of receptor-mediated LDL uptake due to mutations of the LDL receptor, the ApoB protein, the low-density lipoprotein receptor adapter protein 1 (LDLRAP1), or the proprotein convertase subtilisin/kexin type 9 (PCSK9) gene [60].