WNT1 and Parkinson disease: Moreover, miR-34-b/c, which was found to be downregulated in brain areas of PD patients prior to the appearance of motor dysfunction, silences expression of Wnt1 by targeting it at the 3’UTR, and enhances differentiation of murine embryonic stem cells or transdifferentiation of fibroblasts into dopaminergic neurons [107,108].