RAB5A and neoplasm: Conversely, the tumour suppressors CMTM3 and CMTM7 (chemokine-like factor-like MARVEL transmembrane domain-containing 3 and 7) inhibit EGFR-mediated tumorigenicity and EGFR-dependent cell migration by stimulating Rab5 activity, in gastric and lung carcinomas, respectively [50,51].