Twenty-two genes, including SIN3A, BID, HGF, EPOR, CAMK2B, CREB5, PTPN11, NKD1, HNF1A, EFNA2, SMC3, SFRP1, PKMYT1, C19orf40, DDIT3, SOS1, DKK4, PRKAR1B, TNFRSF10A, LAMA1, ITGA2 and PGF were found in the 30 downregulated (in tumor MF) gene list. This evidence concerns the gene ITGA2 and neoplasm.