Similarly, Cheng et al. [69] demonstrated that EVs derived from the OPM2 MM cell line contain high levels of miR-21 and miR-146, which trigger cell proliferation, IL-6 release, and conversion of mesenchymal stromal cells (MSCs) into CAFs, as documented by overexpression of FAP, αSMA, and SDF-1 [69]. The gene discussed is IL6; the disease is Miyoshi myopathy.