A study compared between several pediatric tumors revealed that GBM, neuroblastoma, as well as the embryonic atypical teratoid/rhabdoid tumor, had increased number of TILs along with increased expression of PD-L1 [149], explaining the influx of TILs failed to improve the overall survival of MB patients [150,151]. The gene discussed is CD274; the disease is neuroblastoma.