On the one hand, an increase of c-Myb might correlate with tumor cell ability to seed metastasis [79] as well as with the transcriptional regulation of epithelial genes in association with EMT in BrCa, while the overexpression of GAPDH in the nucleus occurs during apoptosis [80], and it has also been associated with cancer cell senescence [81] or with DNA repair processes [82]. This evidence concerns the gene GAPDH and invasive breast carcinoma.