While exposure to acute hypoxia decreased expression of BER genes MTH1, OGG1 and FEN1, we did not observe differences in the expression of these genes between anoxia-tolerant and oxic control NCI-H460 lung (Figure 2B,C) or T98G glioblastoma (Figure 2E,F) cancer cells in acute hypoxic conditions. The gene discussed is FEN1; the disease is cancer.