Furthermore, we found that the median frequency of BTLA positive Ki67+ B cells in CLL was higher when compared to corresponding cells from healthy donors (p = 0.055) (Figure 6c); while, regarding BTLA negative Ki67+ B cell subset, we showed no statistically significant differences between the examined groups (Figure 6d). The gene discussed is MKI67; the disease is B-cell chronic lymphocytic leukemia.