FOXP3 and retinal ischemia: Our findings are in keeping with published data by others that have demonstrated Tregs act as part of the adaptive immune system, and thereby (A) serve as important regulators of inflammation and play a critical role in immune homeostasis [14]; (B) are inversely correlated with retinal ischemia [34]; and (C) are well known for immunomodulation, with recent evidence suggesting that MSCs can enhance Foxp3+Treg differentiation and stability from activated T cells in part through mitochondrial transfer [12,13,35].