Interestingly, EPS significantly increased mTOR expression in healthy myotubes (p = 0.001) but not in COPD myotubes (Interaction: p = 0.013; Figure 3D), and the variations in mTOR expression were significantly different (p = 0.010; Figure 3E) between the healthy myotubes (+29.7%) and COPD myotubes (+0.9%). The gene discussed is MTOR; the disease is chronic obstructive pulmonary disease.