While EPS had no effect on the expression of the mitochondrial fission marker DRP1 (Figure 5I,J), expression of the fusion marker MFN2 increased significantly in healthy myotubes (p = 0.031; Figure 5G) but not in COPD myotubes after EPS (interaction: p = 0.025; Figure 5G). This evidence concerns the gene MFN2 and chronic obstructive pulmonary disease.