Although limited studies on its role in cancer development and progression are available, PGRMC2 expression, which has been shown to be post-transcriptionally regulated by miR-142-3p [174], is higher in breast cancer tissue compared to non-cancerous one, suggesting its potential contribution to the tumorigenesis of the breast [175] and serving as possible biomarker for breast cancer staging [176]. Here, PGRMC2 is linked to breast carcinoma.