Such interference with hBD-1 levels may enable the parasite to escape the host’s immune defense, while hBD-2 remains ‘in fight’ and its elevated levels indicate a stimulation of part of the immune system and perspectives to effectively eliminate the cause of infection, especially as the effect of AMPs, including hBD-2, in efficiently inactivating C. parvum sporozoites has been reported [59]. The gene discussed is DEFB1; the disease is infection.