In particular, DHA, a semi-synthetic derivative of artemisinin anti-malarial drug, accelerates ferritinophagy through the AMP-activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR)/p70S6k signaling pathway to trigger ferroptosis in acute myeloid leukemia cells [112]. This evidence concerns the gene MTOR and acute myeloid leukemia.