PLA2G6 and Parkinson disease: Mutations of GVI PLA2 gene have been shown to cause a number of neurological abnormalities including infantile neuroaxonal dystrophy (INAD), neurodegeneration with brain iron accumulation (NBIA), autosomal recessive early-onset dystonia-Parkinson disease with Lewy body pathology and accumulation of hyperphosphorylated tau [57,60,63,74].