Some clinical and preclinical studies have identified B7 homolog 3 (B7-H3), EGFRvIII, ephrin type-A receptor 2 (EphA2), HER 2, and IL13Ra2 as promising TAAs overexpressed on some paediatric CNS tumours (see Table 2 and references [81,82,83,84,85,86,87]). Here, CD276 is linked to central nervous system neoplasm.