TAM kinases are overexpressed in numerous cancers, including myeloid and lymphoblastic leukaemia, breast, lung, colon, liver, gastric, kidney and brain cancers [8,9,10]; particularly, both overexpression of AXL and its ligand growth arrest specific 6 (Gas6) have been reported as poor prognosis markers in GBM patients [11]. This evidence concerns the gene GAS6 and glioblastoma.